Stability of monomeric Cro variants: Isoenergetic transformation of a type I to a type II -hairpin by single amino acid replacements

The thermodynamic stabilities of three monomeric variants of the bacteriophage Cro repressor that differ only in the sequence of two amino acids at the apex of an engineered -hairpin have been determined. The sequences of the turns are EVK-XX-EVK, where the two central residues are DG, GG, and GT...

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