Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021
Background Anaemia is a major health problem worldwide. Global estimates of anaemia burden are crucial for developing appropriate interventions to meet current international targets for disease mitigation. We describe the prevalence, years lived with disability, and trends of anaemia and its under...
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| Médium: | Článek |
| Jazyk: | angličtina |
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Lancet Haematol
2025
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| On-line přístup: | https://repository.auw.edu.bd/handle/123456789/1185 |
| _version_ | 1857448929027686400 |
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| author | Alam, Nazmul |
| author_facet | Alam, Nazmul |
| author_sort | Alam, Nazmul |
| collection | institutional Repository |
| description | Background Anaemia is a major health problem worldwide. Global estimates of anaemia burden are crucial for
developing appropriate interventions to meet current international targets for disease mitigation. We describe the
prevalence, years lived with disability, and trends of anaemia and its underlying causes in 204 countries and territories.
Methods We estimated population-level distributions of haemoglobin concentration by age and sex for each location
from 1990 to 2021. We then calculated anaemia burden by severity and associated years lived with disability (YLDs).
With data on prevalence of the causes of anaemia and associated cause-specific shifts in haemoglobin concentrations,
we modelled the proportion of anaemia attributed to 37 underlying causes for all locations, years, and demographics
in the Global Burden of Disease Study 2021.
Findings In 2021, the global prevalence of anaemia across all ages was 24·3% (95% uncertainty interval [UI] 23·9–24·7),
corresponding to 1·92 billion (1·89–1·95) prevalent cases, compared with a prevalence of 28·2% (27·8–28·5)
and 1·50 billion (1·48–1·52) prevalent cases in 1990. Large variations were observed in anaemia burden by age, sex,
and geography, with children younger than 5 years, women, and countries in sub-Saharan Africa and south Asia
being particularly affected. Anaemia caused 52·0 million (35·1–75·1) YLDs in 2021, and the YLD rate due to anaemia
declined with increasing Socio-demographic Index. The most common causes of anaemia YLDs in 2021 were dietary
iron deficiency (cause-specific anaemia YLD rate per 100 000 population: 422·4 [95% UI 286·1–612·9]),
haemoglobinopathies and haemolytic anaemias (89·0 [58·2–123·7]), and other neglected tropical
diseases (36·3 [24·4–52·8]), collectively accounting for 84·7% (84·1–85·2) of anaemia YLDs.
Interpretation Anaemia remains a substantial global health challenge, with persistent disparities according to age,
sex, and geography. Estimates of cause-specific anaemia burden can be used to design locally relevant health
interventions aimed at improving anaemia management and prevention. |
| format | Article |
| id | 123456789-1185 |
| institution | Asian University for Women |
| language | English |
| publishDate | 2025 |
| publisher | Lancet Haematol |
| record_format | dspace |
| spelling | 123456789-11852026-02-18T06:14:55Z Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021 Alam, Nazmul Background Anaemia is a major health problem worldwide. Global estimates of anaemia burden are crucial for developing appropriate interventions to meet current international targets for disease mitigation. We describe the prevalence, years lived with disability, and trends of anaemia and its underlying causes in 204 countries and territories. Methods We estimated population-level distributions of haemoglobin concentration by age and sex for each location from 1990 to 2021. We then calculated anaemia burden by severity and associated years lived with disability (YLDs). With data on prevalence of the causes of anaemia and associated cause-specific shifts in haemoglobin concentrations, we modelled the proportion of anaemia attributed to 37 underlying causes for all locations, years, and demographics in the Global Burden of Disease Study 2021. Findings In 2021, the global prevalence of anaemia across all ages was 24·3% (95% uncertainty interval [UI] 23·9–24·7), corresponding to 1·92 billion (1·89–1·95) prevalent cases, compared with a prevalence of 28·2% (27·8–28·5) and 1·50 billion (1·48–1·52) prevalent cases in 1990. Large variations were observed in anaemia burden by age, sex, and geography, with children younger than 5 years, women, and countries in sub-Saharan Africa and south Asia being particularly affected. Anaemia caused 52·0 million (35·1–75·1) YLDs in 2021, and the YLD rate due to anaemia declined with increasing Socio-demographic Index. The most common causes of anaemia YLDs in 2021 were dietary iron deficiency (cause-specific anaemia YLD rate per 100 000 population: 422·4 [95% UI 286·1–612·9]), haemoglobinopathies and haemolytic anaemias (89·0 [58·2–123·7]), and other neglected tropical diseases (36·3 [24·4–52·8]), collectively accounting for 84·7% (84·1–85·2) of anaemia YLDs. Interpretation Anaemia remains a substantial global health challenge, with persistent disparities according to age, sex, and geography. Estimates of cause-specific anaemia burden can be used to design locally relevant health interventions aimed at improving anaemia management and prevention. 2025-08-12T11:29:42Z 2025-08-12T11:29:42Z 2023 Article https://repository.auw.edu.bd/handle/123456789/1185 en application/pdf Lancet Haematol |
| spellingShingle | Alam, Nazmul Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title | Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_full | Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_fullStr | Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_full_unstemmed | Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_short | Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021 |
| title_sort | prevalence years lived with disability and trends in anaemia burden by severity and cause 1990 2021 findings from the global burden of disease study 2021 |
| url | https://repository.auw.edu.bd/handle/123456789/1185 |
| work_keys_str_mv | AT alamnazmul prevalenceyearslivedwithdisabilityandtrendsinanaemiaburdenbyseverityandcause19902021findingsfromtheglobalburdenofdiseasestudy2021 |