Development of a multi-epitope vaccine candidate against Sindbis virus through integrated immunoinformatics approaches and molecular dynamics simulations

Sindbis virus (SINV), belonging to the genus Alphavirus, is the causative agent of Pogosta disease in humans. The clinical infection is characterized by fever, malaise, rash, myalgia, and arthralgia, which is generally self limiting. Chronic infection with SINV triggers autoimmune conditions that le...

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Autori principali:	Ishaque Ira, Nabila, Jaishee, Nishika, Saha, Ayan, Naidoo, Devashan, Islam, Shazneen Tasnim, Tani, Tazneen Hossain, Roy, Ayan
Natura:	Articolo
Lingua:	inglese
Pubblicazione:	Elsevier 2026
Soggetti:	Sindbis virus Vaccine Multi-epitope Immunoinformatics Molecular docking Molecular dynamics simulations
Accesso online:	https://repository.auw.edu.bd/handle/123456789/3055