Ni2+ Ion Sensing by a Semicarbazone Derivative of Piperidin-4-one: A Spectrofluorimetric Study

Nickel ions are toxic to the environment and they are also relevant in biology. Fluorescence sensing is a sensitive method and metal sensing can be carried out employing cheaper and easy-to-synthesize molecules that possess fluorescence emission. Therefore, the development of newer and simply-synt...

ver descrição completa

Detalhes bibliográficos
Autor principal: Selvakumare, P. Mosae
Formato: Artigo
Idioma:inglês
Publicado em: Iranian Chemical Society 2025
Assuntos:
Acesso em linha:https://repository.auw.edu.bd/handle/123456789/957
_version_ 1857448966647447552
author Selvakumare, P. Mosae
author_facet Selvakumare, P. Mosae
author_sort Selvakumare, P. Mosae
collection institutional Repository
description Nickel ions are toxic to the environment and they are also relevant in biology. Fluorescence sensing is a sensitive method and metal sensing can be carried out employing cheaper and easy-to-synthesize molecules that possess fluorescence emission. Therefore, the development of newer and simply-synthesized chemosensor molecules for nickel ions in aqueous media is required. We report, in this paper, a simple semicarbazone derivative of a piperidin-4-one as a nickel ion sensor in water. The compound forms a 1:1 stoichiometric complex with nickel ions. The association constant value is 4.04 × 104 mol-1 dm3 . The nickel ion-selectivity of the compound is explored employing UV-Vis and fluorescence spectroscopy. Ni2+ ion-chelation enhances the fluorescence of the chemosensor molecule. The Ni2+ detection limit of the chemosensor was 1 × 10-7 mol dm-3 . The compound also forms a 1:2 inclusion complex with β-cyclodextrin. The structure of the complex is proposed. Host: guest complex formation of β-cyclodextrin with the piperidin-4-one derivative results in the interference of the host molecule with the chelation of Ni2+ ions. As an extension of the application of the piperidin-4-one derivative, we demonstrate the Ni(II) ion filtration by incorporating the compound with a polysulfone film.
format Article
id 123456789-957
institution Asian University for Women
language English
publishDate 2025
publisher Iranian Chemical Society
record_format dspace
spelling 123456789-9572026-02-18T06:15:05Z Ni2+ Ion Sensing by a Semicarbazone Derivative of Piperidin-4-one: A Spectrofluorimetric Study Selvakumare, P. Mosae Semicarbazone, Piperidone, Ni2+ sensing, Fluorescent chemosensor, β-Cyclodextrin, Host-guest complex Nickel ions are toxic to the environment and they are also relevant in biology. Fluorescence sensing is a sensitive method and metal sensing can be carried out employing cheaper and easy-to-synthesize molecules that possess fluorescence emission. Therefore, the development of newer and simply-synthesized chemosensor molecules for nickel ions in aqueous media is required. We report, in this paper, a simple semicarbazone derivative of a piperidin-4-one as a nickel ion sensor in water. The compound forms a 1:1 stoichiometric complex with nickel ions. The association constant value is 4.04 × 104 mol-1 dm3 . The nickel ion-selectivity of the compound is explored employing UV-Vis and fluorescence spectroscopy. Ni2+ ion-chelation enhances the fluorescence of the chemosensor molecule. The Ni2+ detection limit of the chemosensor was 1 × 10-7 mol dm-3 . The compound also forms a 1:2 inclusion complex with β-cyclodextrin. The structure of the complex is proposed. Host: guest complex formation of β-cyclodextrin with the piperidin-4-one derivative results in the interference of the host molecule with the chelation of Ni2+ ions. As an extension of the application of the piperidin-4-one derivative, we demonstrate the Ni(II) ion filtration by incorporating the compound with a polysulfone film. 2025-08-04T13:24:13Z 2025-08-04T13:24:13Z 2022 Article https://repository.auw.edu.bd/handle/123456789/957 en application/pdf Iranian Chemical Society
spellingShingle Semicarbazone, Piperidone, Ni2+ sensing, Fluorescent chemosensor, β-Cyclodextrin, Host-guest complex
Selvakumare, P. Mosae
Ni2+ Ion Sensing by a Semicarbazone Derivative of Piperidin-4-one: A Spectrofluorimetric Study
title Ni2+ Ion Sensing by a Semicarbazone Derivative of Piperidin-4-one: A Spectrofluorimetric Study
title_full Ni2+ Ion Sensing by a Semicarbazone Derivative of Piperidin-4-one: A Spectrofluorimetric Study
title_fullStr Ni2+ Ion Sensing by a Semicarbazone Derivative of Piperidin-4-one: A Spectrofluorimetric Study
title_full_unstemmed Ni2+ Ion Sensing by a Semicarbazone Derivative of Piperidin-4-one: A Spectrofluorimetric Study
title_short Ni2+ Ion Sensing by a Semicarbazone Derivative of Piperidin-4-one: A Spectrofluorimetric Study
title_sort ni2 ion sensing by a semicarbazone derivative of piperidin 4 one a spectrofluorimetric study
topic Semicarbazone, Piperidone, Ni2+ sensing, Fluorescent chemosensor, β-Cyclodextrin, Host-guest complex
url https://repository.auw.edu.bd/handle/123456789/957
work_keys_str_mv AT selvakumarepmosae ni2ionsensingbyasemicarbazonederivativeofpiperidin4oneaspectrofluorimetricstudy