Development of a multi-epitope vaccine candidate against Sindbis virus through integrated immunoinformatics approaches and molecular dynamics simulations

Sindbis virus (SINV), belonging to the genus Alphavirus, is the causative agent of Pogosta disease in humans. The clinical infection is characterized by fever, malaise, rash, myalgia, and arthralgia, which is generally self limiting. Chronic infection with SINV triggers autoimmune conditions that le...

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Bibliographic Details

Main Authors:	Ira, Nabila Ishaque, Jaishee, Nishika, Saha, Ayan, Naidoo, Devashan, Islam, Shazneen Tasnim, Tani, Tazneen Hossain, Roy, Ayan
Format:	Article
Language:	English
Published:	Elsevier 2026
Subjects:	Sindbis virus Vaccine Multi-epitope Immunoinformatics Molecular docking Molecular dynamics simulations
Online Access:	https://repository.auw.edu.bd/handle/123456789/3056